What Is ProEpicate® / epicatechin?
The markets most trusted source of Epicatechin
>90% Epicatechin
Below is based on studies and are not to be taken as claims
Educational Notice
This article is provided for general educational and informational purposes only. It discusses ingredient characteristics and published research in a non-therapeutic context and is not intended as medical advice or as a claim of outcomes.
What Is Proepicate®?
Proepicate® is a trademarked, standardised extract of epicatechin derived from cocoa and produced to a purity of greater than 90%.
Cocoa is naturally one of the richest dietary sources of epicatechin, which is why cocoa-derived extracts are commonly used when formulating epicatechin-based ingredients for sports nutrition and performance-focused supplements.
Proepicate® is manufactured using standardisation and microencapsulation technology, processes often employed in supplement formulation to improve ingredient consistency, stability, and handling within multi-ingredient formulas.
Why Standardisation and Source Matter
Epicatechin can be sourced from several plant materials, including cocoa and green tea (Camellia sinensis). However, commercially available epicatechin extracts vary widely in:
Source material
Purity percentage
Processing method
Many epicatechin products on the market are standardised to relatively low active concentrations. In contrast, Proepicate® is produced to a defined specification exceeding 90% epicatechin, allowing formulators to work with a known and consistent ingredient profile.
This level of standardisation helps reduce variability between batches and supports transparent labelling.
Inclusion Levels and Formulation Considerations
Epicatechin has been examined in research settings across a range of inclusion levels. When formulating with high-purity, microencapsulated epicatechin extracts, inclusion amounts are typically selected based on:
The purity of the ingredient
Processing method and encapsulation
Compatibility within the overall formula
Proepicate® is included at an amount intended to align with published research ranges, while also considering formulation balance and synergy with other ingredients.
What Is Epicatechin?
Epicatechin is a naturally occurring flavanol found in foods such as cocoa, tea, and certain fruits. It belongs to a broader class of polyphenolic compounds that have been widely studied in nutritional and physiological research.
Epicatechin has been of interest to researchers due to its interaction with cellular signaling pathways, vascular function, and exercise-related physiological processes.
Research Areas of Interest (Non-Clinical Overview)
Scientific research on epicatechin has explored several areas relevant to exercise and metabolism. These investigations are primarily observational and mechanistic in nature and do not represent therapeutic claims.
Areas that have been examined include:
Muscle-Related Signaling Pathways
Research has explored how epicatechin may influence regulatory proteins involved in muscle protein turnover, including pathways associated with myostatin and follistatin signaling.
Nitric Oxide and Vascular Function
Epicatechin has been studied for its interaction with nitric oxide pathways, which play a role in vascular function and blood flow regulation.
Exercise Capacity and Mitochondrial Function
Some studies have investigated epicatechin’s relationship with mitochondrial biogenesis and endurance-related markers during exercise.
Oxidative Stress and Muscle Recovery
Epicatechin’s antioxidant properties have been examined in relation to oxidative stress following physical exertion.
Metabolic and Cardiometabolic Markers
Research has also explored epicatechin’s interaction with glucose metabolism, lipid markers, and cardiovascular health parameters in non-clinical contexts.
Human Research Context
Small human studies have examined epicatechin supplementation at daily intakes similar to those used in sports nutrition formulations. These studies have varied in design, population, and standardisation of the epicatechin source.
Differences in source material and purity between studies highlight the importance of ingredient standardisation when interpreting research outcomes.
Proepicate® was developed to address this variability by providing a high-purity, clearly defined epicatechin ingredient suitable for consistent formulation.
Proepicate® in Supplement Design
Proepicate® is typically included as part of a broader ingredient system, rather than as a standalone compound. Its role is to complement other formulation components within training-focused supplements.
Microencapsulation and the use of additional bioavailability-focused ingredients are common formulation strategies designed to support ingredient delivery within complex supplement stacks.
Final Thoughts
Proepicate® represents a standardised approach to using epicatechin in sports nutrition formulations. By focusing on source quality, purity, and consistency, it reflects a broader industry trend toward ingredient transparency and formulation precision.
As with all supplement ingredients, epicatechin-based compounds are best understood as part of an overall nutrition and training strategy, rather than as isolated solutions.
As shown Myostatin reduced in the old and young candidates and follistatin increased.
In conclusion this could be a great addition for athletes and bodybuilder which also includes a vast amount of health benifits according to the studies available.
