What is Cardamoxine 6-paradol cardamum extract?
What is CARDAMOXINE™?
6-Paradol CardamoumExtract
Educational Notice
This article is provided for general educational and informational purposes only. It discusses ingredient characteristics and published research in a non-therapeutic context and is not intended as medical advice or as a claim of outcomes.
Cardamoxine®: A Standardised Cardamom Extract Featuring 6-Paradol
Cardamoxine® is a trademarked, standardised extract derived from Elettaria cardamomum, commonly known as cardamom. It is designed to provide a consistent and defined source of 6-Paradol, a naturally occurring bioactive compound found in certain cardamom species.
Rather than relying on raw spice powders or variable extracts, Cardamoxine® is produced to a defined specification to support transparency and formulation consistency in supplement design.
What Is Cardamoxine®?
Cardamoxine® is a high-quality cardamom extract standardised to a defined concentration of 6-Paradol. Standardisation ensures that each batch delivers a consistent profile of active compounds, which is essential when formulating multi-ingredient supplements.
Cardamom has a long history of use in traditional diets and herbal practices, and modern research has focused on isolating specific compounds within cardamom that may be responsible for its biological activity.
Why Standardisation Matters
Cardamom extracts can vary widely depending on:
Plant variety
Growing conditions
Extraction method
Active compound concentration
Many generic extracts contain low or unspecified levels of 6-Paradol. Cardamoxine®, by contrast, is produced to a clearly defined standard, allowing formulators to work with a known and repeatable ingredient profile.
This approach supports ingredient transparency and avoids the variability often seen in non-standardised botanical extracts.
What Is 6-Paradol?
6-Paradol is a bioactive phenolic compound naturally present in certain cardamom species. It has been the subject of scientific interest due to its interaction with metabolic, inflammatory, and cellular signaling pathways.
Research on 6-Paradol has primarily focused on:
Energy metabolism pathways
Thermogenic signaling mechanisms
Antioxidant and anti-inflammatory activity
These investigations are typically conducted in controlled research settings and are used to guide further study and formulation decisions.
Research Areas of Interest (Non-Clinical Overview)
Scientific studies examining 6-Paradol and related cardamom extracts have explored several physiological pathways. These areas of interest include:
Energy Expenditure and Thermogenic Signaling
Some research has investigated how compounds like 6-Paradol interact with pathways involved in energy expenditure and heat production.
Brown Adipose Tissue (BAT) Research
Brown adipose tissue has been studied for its role in thermogenesis. Certain botanical compounds, including those found in cardamom, have been examined for their interaction with BAT-related signaling pathways in research settings.
Antioxidant and Inflammatory Pathways
6-Paradol has been studied for its antioxidant properties and its interaction with inflammatory markers, which are relevant to general metabolic health.
Hormonal and Metabolic Markers
Pre-clinical and limited human research has explored how cardamom-derived compounds may interact with metabolic and hormonal markers under controlled conditions.
These findings are exploratory in nature and do not constitute therapeutic claims.
Human Research Context
Human studies examining cardamom extracts and 6-Paradol have varied in design, duration, and standardisation of the extract used. Differences in extract composition highlight the importance of using standardised ingredients when interpreting research outcomes.
Cardamoxine® was developed to provide a consistent, defined source of 6-Paradol, allowing it to be incorporated into supplement formulations with greater confidence in ingredient composition.
Cardamoxine® in Supplement Formulation
Cardamoxine® is typically used as part of a broader ingredient system, rather than as a standalone component. Inclusion levels are selected based on:
Ingredient purity and standardisation
Overall formulation balance
Compatibility with other ingredients in the stack
Because it is non-stimulant in nature, Cardamoxine® is often considered in formulations designed to complement training, nutrition, and lifestyle strategies without relying on stimulant-based ingredients.
Final Thoughts
Cardamoxine® represents a modern, standardised approach to using cardamom-derived bioactive compounds in supplement formulations. By focusing on ingredient definition, purity, and consistency, it aligns with a broader industry shift toward precision formulation and transparent ingredient selection.
As with all botanical ingredients, cardamom extracts and 6-Paradol are best understood as part of an overall nutrition and lifestyle framework, rather than as isolated solutions.
Fig. 3 Response of energy expenditure (EE) to grains of paradise (GP) extract. The response of EE to GP extract (■) and placebo (□) was calculated as the AUC between 0 and 2 h from the data in Fig. 1. (a) AUC as a whole, (b) AUC adjusted for fat-free-mass (FFM).
